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Blaise Corthésy Selected Research

Secretory Immunoglobulin A (SIgA)

11/2021NOD2 deficiency increases retrograde transport of secretory IgA complexes in Crohn's disease.
11/2013Rotavirus specific plasma secretory immunoglobulin in children with acute gastroenteritis and children vaccinated with an attenuated human rotavirus vaccine.
9/2013Dectin-1 is essential for reverse transcytosis of glycosylated SIgA-antigen complexes by intestinal M cells.
9/2013Secretory IgA induces tolerogenic dendritic cells through SIGNR1 dampening autoimmunity in mice.
8/2013Agglutinating secretory IgA preserves intestinal epithelial cell integrity during apical infection by Shigella flexneri.
4/2013Role of secretory IgA in infection and maintenance of homeostasis.
1/2011Transient suppression of Shigella flexneri type 3 secretion by a protective O-antigen-specific monoclonal IgA.
5/2010Role of secretory immunoglobulin A and secretory component in the protection of mucosal surfaces.
11/2009Secretory IgA-mediated neutralization of Shigella flexneri prevents intestinal tissue destruction by down-regulating inflammatory circuits.
2/2003Recombinant secretory immunoglobulin A in passive immunotherapy: linking immunology and biotechnology.

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Blaise Corthésy Research Topics

Disease

17Infections
01/2018 - 09/2002
4Hypersensitivity (Allergy)
09/2012 - 10/2004
3Bacterial Infections (Bacterial Infection)
01/2018 - 07/2002
3Salmonella Infections (Salmonellosis)
01/2018 - 01/2016
3Inflammation (Inflammations)
01/2017 - 11/2009
3Autoimmune Diseases (Autoimmune Disease)
09/2013 - 04/2011
2Neoplasms (Cancer)
09/2012 - 05/2010
1Crohn Disease (Crohn's Disease)
11/2021
1Asthma (Bronchial Asthma)
10/2017
1Gastroenteritis
11/2013
1Melanoma (Melanoma, Malignant)
10/2013
1Communicable Diseases (Infectious Diseases)
09/2013
1Type 1 Diabetes Mellitus (Autoimmune Diabetes)
09/2013
1Multiple Sclerosis
09/2013
1Bacillary Dysentery (Shigellosis)
08/2013
1Porcine Reproductive and Respiratory Syndrome (PRRS)
04/2012
1Food Hypersensitivity (Food Allergy)
04/2006
1Pyelonephritis
12/2005
1Gastritis
10/2005
1Adenocarcinoma
10/2005
1Peptic Ulcer (Peptic Ulcers)
10/2005
1Anaphylaxis (Anaphylactic Shock)
10/2004
1Sepsis (Septicemia)
02/2004
1Abscess
02/2004
1Stroke (Strokes)
02/2003
1Milk Hypersensitivity (Milk Allergy)
06/2002
1Diarrhea
03/2002

Drug/Important Bio-Agent (IBA)

10Secretory Immunoglobulin A (SIgA)IBA
11/2021 - 02/2003
6AntigensIBA
01/2018 - 04/2011
6Immunoglobulin A (IgA)IBA
01/2018 - 07/2002
6VaccinesIBA
01/2016 - 03/2002
4Immunoglobulins (Immunoglobulin)IBA
01/2018 - 02/2013
4Proteins (Proteins, Gene)FDA Link
01/2016 - 09/2002
3AntibodiesIBA
01/2018 - 02/2003
3OvalbuminIBA
10/2017 - 07/2013
2Antigen-Antibody Complex (Immune Complex)IBA
11/2021 - 11/2009
2Immunoglobulin M (IgM)IBA
01/2018 - 01/2017
2AllergensIBA
10/2017 - 06/2002
2Poly I-CIBA
10/2013 - 04/2011
2DNA (Deoxyribonucleic Acid)IBA
10/2005 - 10/2004
1LipidsIBA
01/2018
1Immunoglobulin G (IgG)IBA
01/2018
1Anti-Bacterial Agents (Antibiotics)IBA
01/2017
1Secretory ComponentIBA
01/2017
1IgA receptor (protein B)IBA
01/2016
1Subunit VaccinesIBA
07/2015
1Monoclonal AntibodiesIBA
08/2014
1Rotavirus VaccinesIBA
11/2013
1Toll-Like Receptor 3IBA
10/2013
1Interferon Type IIBA
10/2013
1Phenobarbital (Luminal)FDA Link
08/2013
1Pattern Recognition ReceptorsIBA
04/2012
1ProteomeIBA
04/2011
1Biomarkers (Surrogate Marker)IBA
04/2011
1Peptides (Polypeptides)IBA
05/2010
1Food IngredientsIBA
04/2006
1UreaseIBA
10/2005
1Interleukin-4 (Interleukin 4)IBA
10/2004
1Interleukin-10 (Interleukin 10)IBA
10/2004
1Virulence Factors (Pathogenicity Factors)IBA
02/2004
1Polysaccharides (Glycans)IBA
02/2004
1polymeric IgAIBA
07/2002
1Lactoglobulins (beta-Lactoglobulin)FDA Link
06/2002
1AntitoxinsIBA
03/2002

Therapy/Procedure

5Microbubbles
10/2017 - 07/2013
3Intranasal Administration
10/2017 - 01/2012
2Oral Administration
01/2018 - 01/2017
1Intravenous Administration
08/2014
1Immunotherapy
02/2013
1Secondary Prevention
04/2011
1Therapeutics
04/2006
1Microspheres (Microsphere)
10/2004